Author: David Alsteens

Author: David Alsteens

Milagros Sempere Borau, Victor G. Gisbert, Josephine von Kempis, Laura M. Arroyo-Fernández, Samira Schiefer, David Alsteens, Silke Stertz

PLoS Pathogens (2025),21(7): e1013338→Link

Postdoc in Tumor-Immune Crosstalk and Signaling Dynamics

The NanoBiophysics Lab at UCLouvain is seeking a dynamic and motivated postdoctoral researcher to join a multidisciplinary team investigating tumor-immune system interactions through a biophysical lens. This project aims to understand how properties of the tumor microenvironment influence immune cell behavior, with a focus on immune receptor and downstream signalling protein recruitment in different biophysical contexts. The ultimate goal is to identify new therapeutic strategies to counteract tumor-induced immunosuppression.

The successful candidate will combine molecular biology, immunological assays, and cutting-edge biophysical techniques to explore how immune cells sense and respond to tumor-associated signals. The research will involve fluorescence-activated cell sorting (FACS),  confocal imaging and various biophysical techniques, to characterize immune phenotypes and their mechanical, structural, and molecular interactions within the tumor microenvironment.

Qualifications:

•    A PhD in molecular biology, immunology, cancer biology or a related field.
•    Hands-on experience with FACS and standard molecular biology techniques (e.g., PCR, ELISA, RNA sequencing).
•    A strong background in immunological assays and immune cell phenotyping.
•    Interest in biophysical methods 
•    Excellent organizational, analytical, and communication skills.

Please send your application including a cover letter explaining your background, a CV and names and contact details of 2-3 references by E-mail

Student in Bio-engineering

Place Croix du Sud 4-5, bte L7.07.07 1348 Louvain-La Neuve Belgium

E-mail: camille.lemmens@student.uclouvain.be

Tel. + 32 (0)10/47.35.88

PhD Student (FRIA)

Place Croix du Sud 4-5, bte L7.07.07 1348 Louvain-La Neuve Belgium

E-mail: sarah.mannaert@uclouvain.be

Tel. + 32 (0)10/47.86.63

Postdoctoral fellow of the FNRS

Place Croix du Sud 4-5, bte L7.07.07 1348 Louvain-La Neuve Belgium

E-mail: natalia.martin@uclouvain.be

Tel. + 32 (0)10/47.30.61

Postdoctoral researcher

Place Croix du Sud 4-5, bte L7.07.07 1348 Louvain-La Neuve Belgium

E-mail: telmo.oliveira@uclouvain.be

Tel. + 32 (0)10/47.30.61

A big thank you for this visit and for sharing your knowledge with us! Looking forward to future discussions and collaborations.

We were delighted to welcome Robb de Vries from Utrecht University (Netherlands) for a visit and seminar at our institute. His expertise in virus-glycan interactions provided fascinating insights into how viruses engage with different glycan structures.

Ankita Ray, Joshua D. Simpson, Irem Demir, Victor G. Gisbert, D B. Gomes, Federico Amadei, David Alsteens.

Journal of Virology (2025),99(1): e00873-24.→Link

Qingrong Zhang, Raissa S.L. Rosa, Ankita Ray, Kimberley Durlet, Gol M. Dorrazehi, Rafael C. Bernardi, David Alsteens

Nature Communications (2025), 16, 6 → Link

We had the pleasure of starting the year with a visit from Prof. Rafael Bernardi from Auburn University! After collaborating remotely for quite some time, it was a true privilege to finally interact in person. Prof. Bernardi delivered a memorable presentation that captivated everyone in the lab. The rest of the day was filled with enriching discussions, providing invaluable insights and inspiration for our researchers. We are deeply grateful for his visit and look forward to continuing this fruitful collaboration!